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Use of NMR Saturation Transfer Difference Spectroscopy to Study Ligand Binding to Membrane Proteins
Detection of weak ligand binding to membrane-spanning proteins, such as receptor proteins at low physiological concentrations, poses serious experimental challenges. Saturation transfer difference nuclear magnetic resonance (STD-NMR) spectroscopy offers an excellent way to surmount these problems. A...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3758666/ https://ncbi.nlm.nih.gov/pubmed/22976022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-023-6_4 |
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