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A COVID moonshot: assessment of ligand binding to the SARS-CoV-2 main protease by saturation transfer difference NMR spectroscopy

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological cause of the coronavirus disease 2019, for which no effective antiviral therapeutics are available. The SARS-CoV-2 main protease (M(pro)) is essential for viral replication and constitutes a promising therapeutic target....

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Detalhes bibliográficos
Publicado no:J Biomol NMR
Main Authors: Kantsadi, Anastassia L., Cattermole, Emma, Matsoukas, Minos-Timotheos, Spyroulias, Georgios A., Vakonakis, Ioannis
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047523/
https://ncbi.nlm.nih.gov/pubmed/33856612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-021-00365-x
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