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The telomere-associated homeobox-containing protein TAH1/HMBOX1 participates in telomere maintenance in ALT cells

The majority of cancer cells rely on elevated telomerase expression and activity for rapid growth and proliferation. Telomerase-negative cancer cells, by contrast, often employ the alternative lengthening of telomeres (ALT) pathway to maintain telomeres. ALT cells are characterized by long and dynam...

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Detalhes bibliográficos
Main Authors: Feng, Xuyang, Luo, Zhenhua, Jiang, Shuai, Li, Feng, Han, Xin, Hu, Yang, Wang, Dan, Zhao, Yong, Ma, Wenbin, Liu, Dan, Huang, Junjiu, Songyang, Zhou
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757334/
https://ncbi.nlm.nih.gov/pubmed/23813958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.128512
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