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Telomere Maintenance through Spatial Control of Telomeric Proteins

The six human telomeric proteins TRF1, TRF2, RAP1, TIN2, POT1, and TPP1 can form a complex called the telosome/shelterin, which is required for telomere protection and length control. TPP1 has been shown to regulate both POT1 telomere localization and telosome assembly through its binding to TIN2. I...

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Autors principals: Chen, Liuh-Yow, Liu, Dan, Songyang, Zhou
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952115/
https://ncbi.nlm.nih.gov/pubmed/17562870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00603-07
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