A critical role of telomere chromatin compaction in ALT tumor cell growth

ALT tumor cells often contain abundant DNA damage foci at telomeres and rely on the alternative lengthening of telomeres (ALT) mechanism to maintain their telomeres. How the telomere chromatin is regulated and maintained in these cells remains largely unknown. In this study, we present evidence that...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Shi, Guang, Hu, Yang, Zhu, Xing, Jiang, Yuanling, Pang, Junjie, Wang, Chuanle, Huang, Wenjun, Zhao, Yong, Ma, Wenbin, Liu, Dan, Huang, Junjiu, Songyang, Zhou
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Genome Integrity, Repair and Replication
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293046/
https://ncbi.nlm.nih.gov/pubmed/32379321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa224
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