TOE1 acts as a 3′ exonuclease for telomerase RNA and regulates telomere maintenance

In human cells, telomeres are elongated by the telomerase complex that contains the reverse transcriptase hTERT and RNA template TERC/hTR. Poly(A)-specific ribonuclease (PARN) is known to trim hTR precursors by removing poly(A) tails. However, the precise mechanism of hTR 3′ maturation remains large...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Deng, Tingting, Huang, Yan, Weng, Kai, Lin, Song, Li, Yujing, Shi, Guang, Chen, Yali, Huang, Junjiu, Liu, Dan, Ma, Wenbin, Songyang, Zhou
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
RNA Prot Comp
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326811/
https://ncbi.nlm.nih.gov/pubmed/30371886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1019
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados