Human cells lacking coilin and Cajal bodies are proficient in telomerase assembly, trafficking and telomere maintenance

The RNA component of human telomerase (hTR) localizes to Cajal bodies, and it has been proposed that Cajal bodies play a role in the assembly of telomerase holoenzyme and telomerase trafficking. Here, the role of Cajal bodies was examined in Human cells deficient of coilin (i.e. coilin-knockout (KO)...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Chen, Yanlian, Deng, Zhiqiang, Jiang, Shuai, Hu, Qian, Liu, Haiying, Songyang, Zhou, Ma, Wenbin, Chen, Shi, Zhao, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288172/
https://ncbi.nlm.nih.gov/pubmed/25477378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1277
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