Human cells lacking coilin and Cajal bodies are proficient in telomerase assembly, trafficking and telomere maintenance

The RNA component of human telomerase (hTR) localizes to Cajal bodies, and it has been proposed that Cajal bodies play a role in the assembly of telomerase holoenzyme and telomerase trafficking. Here, the role of Cajal bodies was examined in Human cells deficient of coilin (i.e. coilin-knockout (KO)...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Chen, Yanlian, Deng, Zhiqiang, Jiang, Shuai, Hu, Qian, Liu, Haiying, Songyang, Zhou, Ma, Wenbin, Chen, Shi, Zhao, Yong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
Molecular Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288172/
https://ncbi.nlm.nih.gov/pubmed/25477378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1277
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