Human cells lacking coilin and Cajal bodies are proficient in telomerase assembly, trafficking and telomere maintenance

The RNA component of human telomerase (hTR) localizes to Cajal bodies, and it has been proposed that Cajal bodies play a role in the assembly of telomerase holoenzyme and telomerase trafficking. Here, the role of Cajal bodies was examined in Human cells deficient of coilin (i.e. coilin-knockout (KO)...

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Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Chen, Yanlian, Deng, Zhiqiang, Jiang, Shuai, Hu, Qian, Liu, Haiying, Songyang, Zhou, Ma, Wenbin, Chen, Shi, Zhao, Yong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2015
Onderwerpen:
Molecular Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288172/
https://ncbi.nlm.nih.gov/pubmed/25477378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1277
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