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Genetic Reduction of the α1 Subunit of Na/K-ATPase Corrects Multiple Hippocampal Phenotypes in Angelman Syndrome

Angelman syndrome (AS) is associated with symptoms that include autism, intellectual disability, motor abnormalities, and epilepsy. We recently showed that AS model mice have increased expression of the alpha1 subunit of Na/K-ATPase (α1-NaKA) in the hippocampus, which was correlated with increased e...

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Detalhes bibliográficos
Main Authors: Kaphzan, Hanoch, Buffington, Shelly A., Ramaraj, Akila B., Lingrel, Jerry B., Rasband, Matthew N., Santini, Emanuela, Klann, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756897/
https://ncbi.nlm.nih.gov/pubmed/23911285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.07.005
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