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Chronic α1-Na/K-ATPase inhibition reverses the elongation of the axon initial segment of the hippocampal CA1 pyramidal neurons in Angelman syndrome model mice

Angelman syndrome (AS) is a neurodevelopmental disorder caused by the loss of function of the maternal UBE3A gene. The hippocampus is one of the most prominently affected brain regions in AS model mice, manifesting in severe hippocampal-dependent memory and plasticity deficits. Previous studies in A...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Rayi, Prudhvi Raj, Bagrov, Alexei Y., Kaphzan, Hanoch
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027375/
https://ncbi.nlm.nih.gov/pubmed/33214655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-020-00907-1
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