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Structural and Thermodynamic Basis of (+)-α-Pinene Binding to Human Cytochrome P450 2B6

Despite recent advances in atomic level understanding of drug and inhibitor interactions with human cytochromes P450, the decades-old questions of chemical and structural determinants of hydrocarbon binding are still unanswered. (+)-α-Pinene is a monoterpene hydrocarbon that is widely distributed in...

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Autors principals: Wilderman, P. Ross, Shah, Manish B., Jang, Hyun-Hee, Stout, C. David, Halpert, James R.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754432/
https://ncbi.nlm.nih.gov/pubmed/23786449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja403042k
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