X-ray Crystal Structure of the Cytochrome P450 2B4 Active Site Mutant F297A in Complex with Clopidogrel: Insights into Compensatory Rearrangements of the Binding Pocket()

Documenti analoghi

• Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains
  di: Shah, Manish B., et al.
  Pubblicazione: (2011)
• Effect of Detergent Binding on Cytochrome P450 2B4 Structure as Analyzed by X-ray Crystallography and Deuterium-Exchange Mass Spectrometry
  di: Shah, Manish B., et al.
  Pubblicazione: (2016)
• Conformational Adaptation of Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4 Revealed Upon Binding Multiple Amlodipine Molecules()
  di: Shah, Manish B., et al.
  Pubblicazione: (2012)
• Structures of Cytochrome P450 2B4 Complexed with the Antiplatelet Drugs Ticlopidine and Clopidogrel
  di: Gay, Sean C., et al.
  Pubblicazione: (2010)
• Halogen-π Interactions in the Cytochrome P450 Active Site: Structural Insights into Human CYP2B6 Substrate Selectivity
  di: Shah, Manish B., et al.
  Pubblicazione: (2017)