Structures of Cytochrome P450 2B4 Complexed with the Antiplatelet Drugs Ticlopidine and Clopidogrel

Antzeko izenburuak

• Comparison of In Vitro Metabolism of Ticlopidine by Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4
  nork: Talakad, Jyothi C., et al.
  Argitaratua: (2011)
• Crystal Structure of a Cytochrome P450 2B6 Genetic Variant in Complex with the Inhibitor 4-(4-Chlorophenyl)imidazole at 2.0-Å Resolution
  nork: Gay, Sean C., et al.
  Argitaratua: (2010)
• Crystal structures of cytochrome P450 2B4 in complex with the inhibitor 1-biphenyl-4-methyl-1H–imidazole: ligand induced structural response through α-helical repositioning
  nork: Gay, Sean C., et al.
  Argitaratua: (2009)
• Structural Features of Cytochromes P450 and Ligands that Affect Drug Metabolism as Revealed by X-ray Crystallography and NMR
  nork: Gay, Sean C., et al.
  Argitaratua: (2010)
• X-ray Crystal Structure of the Cytochrome P450 2B4 Active Site Mutant F297A in Complex with Clopidogrel: Insights into Compensatory Rearrangements of the Binding Pocket()
  nork: Shah, Manish B., et al.
  Argitaratua: (2013)