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Small-Molecule Inhibitors of Lethal Factor Protease Activity Protect against Anthrax Infection
Bacillus anthracis, the causative agent of anthrax, manifests its pathogenesis through the action of two secreted toxins. The bipartite lethal and edema toxins, a combination of lethal factor or edema factor with the protein protective antigen, are important virulence factors for this bacterium. We...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3754358/ https://ncbi.nlm.nih.gov/pubmed/23774434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00941-13 |
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