Evaluation of Combinations of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine with Clinically Used Antiretroviral Drugs

Drug combination studies of 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) with FDA-approved drugs were evaluated by two different methods, MacSynergy II and CalcuSyn. Most of the combinations, including the combination of the two adenosine analogs EFdA and tenofovir, were essentially additive, withou...

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Auteurs principaux: Hachiya, Atsuko, Reeve, Aaron B., Marchand, Bruno, Michailidis, Eleftherios, Ong, Yee Tsuey, Kirby, Karen A., Leslie, Maxwell D., Oka, Shinichi, Kodama, Eiichi N., Rohan, Lisa C., Mitsuya, Hiroaki, Parniak, Michael A., Sarafianos, Stefan G.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
Sujets:
Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754316/
https://ncbi.nlm.nih.gov/pubmed/23796932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00283-13
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