Evaluation of Combinations of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine with Clinically Used Antiretroviral Drugs

Drug combination studies of 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) with FDA-approved drugs were evaluated by two different methods, MacSynergy II and CalcuSyn. Most of the combinations, including the combination of the two adenosine analogs EFdA and tenofovir, were essentially additive, withou...

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Hauptverfasser: Hachiya, Atsuko, Reeve, Aaron B., Marchand, Bruno, Michailidis, Eleftherios, Ong, Yee Tsuey, Kirby, Karen A., Leslie, Maxwell D., Oka, Shinichi, Kodama, Eiichi N., Rohan, Lisa C., Mitsuya, Hiroaki, Parniak, Michael A., Sarafianos, Stefan G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754316/
https://ncbi.nlm.nih.gov/pubmed/23796932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00283-13
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