Evaluation of Combinations of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine with Clinically Used Antiretroviral Drugs

Drug combination studies of 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) with FDA-approved drugs were evaluated by two different methods, MacSynergy II and CalcuSyn. Most of the combinations, including the combination of the two adenosine analogs EFdA and tenofovir, were essentially additive, withou...

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Autors principals: Hachiya, Atsuko, Reeve, Aaron B., Marchand, Bruno, Michailidis, Eleftherios, Ong, Yee Tsuey, Kirby, Karen A., Leslie, Maxwell D., Oka, Shinichi, Kodama, Eiichi N., Rohan, Lisa C., Mitsuya, Hiroaki, Parniak, Michael A., Sarafianos, Stefan G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754316/
https://ncbi.nlm.nih.gov/pubmed/23796932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00283-13
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