Llwytho...
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
Hypoxia occurs frequently in human cancers and induces adaptive changes in cell metabolism that include a switch from oxidative phosphorylation to glycolysis, increased glycogen synthesis, and a switch from glucose to glutamine as the major substrate for fatty acid synthesis. This broad metabolic re...
Wedi'i Gadw mewn:
| Prif Awdur: | |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Society for Clinical Investigation
2013
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3754249/ https://ncbi.nlm.nih.gov/pubmed/23999440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67230 |
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