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Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia

Autophagy is a process by which cytoplasmic organelles can be catabolized either to remove defective structures or as a means of providing macromolecules for energy generation under conditions of nutrient starvation. In this study we demonstrate that mitochondrial autophagy is induced by hypoxia, th...

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Autors principals: Zhang, Huafeng, Bosch-Marce, Marta, Shimoda, Larissa A., Tan, Yee Sun, Baek, Jin Hyen, Wesley, Jacob B., Gonzalez, Frank J., Semenza, Gregg L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447655/
https://ncbi.nlm.nih.gov/pubmed/18281291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800102200
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