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Mitochondrial autophagy: life and breath of the cell

Homeostatic responses to reduced O(2) availability are regulated by the transcriptional activator hypoxia-inducible factor 1 (HIF-1) in all metazoan species. An essential adaptation to sustained hypoxia is an active repression of mitochondrial respiration. In mouse embryo fibroblasts, HIF-1 induces...

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Bibliografiske detaljer
Hovedforfatter: Semenza, Gregg L.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738642/
https://ncbi.nlm.nih.gov/pubmed/18376135
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