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HIF and pulmonary vascular responses to hypoxia

In the lung, acute reductions in oxygen lead to hypoxic pulmonary vasoconstriction, whereas prolonged exposures to hypoxia result in sustained vasoconstriction, pulmonary vascular remodeling, and the development of pulmonary hypertension. Data from both human subjects and animal models implicate a r...

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Bibliografiske detaljer
Main Authors: Shimoda, Larissa A., Laurie, Steven S.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972740/
https://ncbi.nlm.nih.gov/pubmed/24336881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00643.2013
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