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HIF and pulmonary vascular responses to hypoxia

In the lung, acute reductions in oxygen lead to hypoxic pulmonary vasoconstriction, whereas prolonged exposures to hypoxia result in sustained vasoconstriction, pulmonary vascular remodeling, and the development of pulmonary hypertension. Data from both human subjects and animal models implicate a r...

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Autori principali: Shimoda, Larissa A., Laurie, Steven S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972740/
https://ncbi.nlm.nih.gov/pubmed/24336881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00643.2013
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