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55th Bowditch Lecture: Effects of chronic hypoxia on the pulmonary circulation: Role of HIF-1

When exposed to chronic hypoxia (CH), the pulmonary circulation responds with enhanced contraction and vascular remodeling, resulting in elevated pulmonary arterial pressures. Our work has identified CH-induced alterations in the expression and activity of several ion channels and transporters in pu...

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Bibliographic Details
Main Author: Shimoda, Larissa A.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524672/
https://ncbi.nlm.nih.gov/pubmed/22923506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00843.2012
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