Type III TGF-β receptor downregulation generates an immunotolerant tumor microenvironment

Cancers subvert the host immune system to facilitate disease progression. These evolved immunosuppressive mechanisms are also implicated in circumventing immunotherapeutic strategies. Emerging data indicate that local tumor-associated DC populations exhibit tolerogenic features by promoting Treg dev...

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書誌詳細
主要な著者: Hanks, Brent A., Holtzhausen, Alisha, Evans, Katherine S., Jamieson, Rebekah, Gimpel, Petra, Campbell, Olivia M., Hector-Greene, Melissa, Sun, Lihong, Tewari, Alok, George, Amanda, Starr, Mark, Nixon, Andrew, Augustine, Christi, Beasley, Georgia, Tyler, Douglas S., Osada, Takayu, Morse, Michael A., Ling, Leona, Lyerly, H. Kim, Blobe, Gerard C.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2013
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754240/
https://ncbi.nlm.nih.gov/pubmed/23925295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65745
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