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The double-stranded RNA binding domain of human Dicer functions as a nuclear localization signal
Dicer is a key player in microRNA (miRNA) and RNA interference (RNAi) pathways, processing miRNA precursors and double-stranded RNA into ∼21-nt-long products ultimately triggering sequence-dependent gene silencing. Although processing of substrates in vertebrate cells occurs in the cytoplasm, there...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753931/ https://ncbi.nlm.nih.gov/pubmed/23882114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.039255.113 |
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