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ATP modulates siRNA interactions with an endogenous human Dicer complex
Short interfering RNA (siRNA) binding by Dicer is important for RNA interference in Drosophila, but human Dicer (hDcr) has been reported to lack siRNA binding activity. We used native gel electrophoresis to characterize the siRNA-binding activity of endogenous hDcr-containing complexes in extracts f...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Copyright 2005 by RNA Society
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370858/ https://ncbi.nlm.nih.gov/pubmed/16177131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2102805 |
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