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siRNA Repositioning for Guide Strand Selection by Human Dicer Complexes
The human ribonuclease Dicer and its double-stranded RNA (dsRNA) binding protein (dsRBP) partners TRBP and PACT play important roles in the biogenesis of regulatory RNAs. Following dicing, one dsRNA product strand is preferentially assembled into an RNA-Induced Silencing Complex (RISC). The mechanis...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3143821/ https://ncbi.nlm.nih.gov/pubmed/21726814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.05.028 |
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