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C/EBPγ Suppresses Senescence and Inflammatory Gene Expression by Heterodimerizing with C/EBPβ
C/EBPβ is an important regulator of oncogene-induced senescence (OIS). Here, we show that C/EBPγ, a heterodimeric partner of C/EBPβ whose biological functions are not well understood, inhibits cellular senescence. Cebpg(−/−) mouse embryonic fibroblasts (MEFs) proliferated poorly, entered senescence...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753923/ https://ncbi.nlm.nih.gov/pubmed/23775115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01674-12 |
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