Epigenetic Functions of Smchd1 Repress Gene Clusters on the Inactive X Chromosome and on Autosomes

The Smchd1 gene encodes a large protein with homology to the SMC family of proteins involved in chromosome condensation and cohesion. Previous studies have found that Smchd1 has an important role in CpG island (CGI) methylation on the inactive X chromosome (Xi) and in stable silencing of some Xi gen...

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Hauptverfasser: Gendrel, Anne-Valerie, Tang, Y. Amy, Suzuki, Masako, Godwin, Jonathan, Nesterova, Tatyana B., Greally, John M., Heard, Edith, Brockdorff, Neil
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753908/
https://ncbi.nlm.nih.gov/pubmed/23754746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00145-13
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