Smchd1-Dependent and -Independent Pathways Determine Developmental Dynamics of CpG Island Methylation on the Inactive X Chromosome

X chromosome inactivation involves multiple levels of chromatin modification, established progressively and in a stepwise manner during early development. The chromosomal protein Smchd1 was recently shown to play an important role in DNA methylation of CpG islands (CGIs), a late step in the X inacti...

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Hoofdauteurs: Gendrel, Anne-Valerie, Apedaile, Anwyn, Coker, Heather, Termanis, Ausma, Zvetkova, Ilona, Godwin, Jonathan, Tang, Y. Amy, Huntley, Derek, Montana, Giovanni, Taylor, Steven, Giannoulatou, Eleni, Heard, Edith, Stancheva, Irina, Brockdorff, Neil
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437444/
https://ncbi.nlm.nih.gov/pubmed/22841499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.06.011
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