Independent Mechanisms Target SMCHD1 to Trimethylated Histone H3 Lysine 9-Modified Chromatin and the Inactive X Chromosome

The chromosomal protein SMCHD1 plays an important role in epigenetic silencing at diverse loci, including the inactive X chromosome, imprinted genes, and the facioscapulohumeral muscular dystrophy locus. Although homology with canonical SMC family proteins suggests a role in chromosome organization,...

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Udgivet i:Mol Cell Biol
Main Authors: Brideau, Nicholas J., Coker, Heather, Gendrel, Anne-Valerie, Siebert, C. Alistair, Bezstarosti, Karel, Demmers, Jeroen, Poot, Raymond A., Nesterova, Tatyana B., Brockdorff, Neil
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628070/
https://ncbi.nlm.nih.gov/pubmed/26391951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00432-15
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