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Early Loss of Xist RNA Expression and Inactive X Chromosome Associated Chromatin Modification in Developing Primordial Germ Cells

BACKGROUND: The inactive X chromosome characteristic of female somatic lineages is reactivated during development of the female germ cell lineage. In mouse, analysis of protein products of X-linked genes and/or transgenes located on the X chromosome has indicated that reactivation occurs after primo...

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Detalhes bibliográficos
Main Authors: de Napoles, Mariana, Nesterova, Tatyana, Brockdorff, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959243/
https://ncbi.nlm.nih.gov/pubmed/17848991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000860
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