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Functional interactions of voltage sensor charges with an S2 hydrophobic plug in hERG channels
Human ether-à-go-go–related gene (hERG, Kv11.1) potassium channels have unusually slow activation and deactivation kinetics. It has been suggested that, in fast-activating Shaker channels, a highly conserved Phe residue (F290) in the S2 segment forms a putative gating charge transfer center that int...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753600/ https://ncbi.nlm.nih.gov/pubmed/23980197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201310992 |
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