Functional interactions of voltage sensor charges with an S2 hydrophobic plug in hERG channels

Human ether-à-go-go–related gene (hERG, Kv11.1) potassium channels have unusually slow activation and deactivation kinetics. It has been suggested that, in fast-activating Shaker channels, a highly conserved Phe residue (F290) in the S2 segment forms a putative gating charge transfer center that int...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Cheng, Yen May, Hull, Christina M., Niven, Christine M., Qi, Ji, Allard, Charlene R., Claydon, Tom W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2013
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753600/
https://ncbi.nlm.nih.gov/pubmed/23980197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201310992
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk