Yüklüyor......
Extracellular protons accelerate hERG channel deactivation by destabilizing voltage sensor relaxation
hERG channels underlie the delayed-rectifier K(+) channel current (I(Kr)), which is crucial for membrane repolarization and therefore termination of the cardiac action potential. hERG channels display unusually slow deactivation gating, which contributes to a resurgent current upon repolarization an...
Kaydedildi:
| Yayımlandı: | J Gen Physiol |
|---|---|
| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Rockefeller University Press
2019
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6363419/ https://ncbi.nlm.nih.gov/pubmed/30530765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812137 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|