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Islet amyloid: From fundamental biophysics to mechanisms of cytotoxicity
Pancreatic islet amyloid is a characteristic feature of type 2 diabetes. The major protein component of islet amyloid is the polypeptide hormone known as islet amyloid polypeptide (IAPP, or amylin). IAPP is stored with insulin in the β-cell secretory granules and is released in response to the stimu...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753196/ https://ncbi.nlm.nih.gov/pubmed/23380070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2013.01.046 |
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