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Intronic Splicing Enhancers, Cognate Splicing Factors and Context Dependent Regulation Rules
Most human genes produce multiple splicing isoforms with distinct functions. To systematically understand splicing regulation, we conducted an unbiased screen and identified >100 intronic splicing enhancers (ISEs) that were clustered by sequence similarity into six groups. All ISEs functioned in...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753194/ https://ncbi.nlm.nih.gov/pubmed/22983564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2377 |
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