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A Complex Network of Factors with Overlapping Affinities Repress Splicing through Intronic Elements

To better understand splicing regulation, we used a cell-based screen to identify ten diverse motifs that inhibit splicing from intron. Each motif was validated in another human cell type and gene context, and their presence correlated with in vivo splicing changes. All motifs exhibited exonic splic...

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Autors principals: Wang, Yang, Xiao, Xinshu, Zhang, Jianming, Choudhury, Rajarshi, Robertson, Alex, Li, Kai, Ma, Meng, Burge, Christopher B., Wang, Zefeng
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537874/
https://ncbi.nlm.nih.gov/pubmed/23241926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2459
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