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Inhibitory role of the transcription repressor Gfi1 in the generation of thymus-derived regulatory T cells

Foxp3(+) regulatory T (T(reg)) cells are essential for the maintenance of self-tolerance and immune homeostasis. The majority of T(reg) cells is generated in the thymus as a specific subset of CD4(+) T cells, known as thymus-derived or natural T(reg) (nT(reg)) cells, in response to signals from T-ce...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Shi, Lewis Zhichang, Kalupahana, Nishan S., Turnis, Meghan E., Neale, Geoffrey, Hock, Hanno, Vignali, Dario A. A., Chi, Hongbo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752244/
https://ncbi.nlm.nih.gov/pubmed/23918371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300950110
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