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Gfi1-Foxo1 axis controls the fidelity of effector gene expression and developmental maturation of thymocytes
Double-positive (DP) thymocytes respond to intrathymic T-cell receptor (TCR) signals by undergoing positive selection and lineage differentiation into single-positive (SP) mature cells. Concomitant with these well-characterized events is the acquisition of a mature T-cell gene expression program cha...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5224387/ https://ncbi.nlm.nih.gov/pubmed/27994150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1617669114 |
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