Transforming growth factor beta-activated kinase 1 (TAK1)-dependent checkpoint in the survival of dendritic cells promotes immune homeostasis and function

Homeostatic control of dendritic cell (DC) survival is crucial for adaptive immunity, but the molecular mechanism is not well defined. Moreover, how DCs influence immune homeostasis under steady state remains unclear. Combining DC-specific and -inducible deletion systems, we report that transforming...

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Bibliographic Details
Main Authors: Wang, Yanyan, Huang, Gonghua, Vogel, Peter, Neale, Geoffrey, Reizis, Boris, Chi, Hongbo
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277515/
https://ncbi.nlm.nih.gov/pubmed/22308391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115635109
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