Progranulin Is a Novel Independent Predictor of Disease Progression and Overall Survival in Chronic Lymphocytic Leukemia

Progranulin (Pgrn) is a 88 kDa secreted protein with pleiotropic functions including regulation of cell cycle progression, cell motility, wound repair and tumorigenesis. Using microarray based gene expression profiling we have recently demonstrated that the gene for Pgrn, granulin (GRN), is signific...

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主要な著者: Göbel, Maria, Eisele, Lewin, Möllmann, Michael, Hüttmann, Andreas, Johansson, Patricia, Scholtysik, René, Bergmann, Manuela, Busch, Raymonde, Döhner, Hartmut, Hallek, Michael, Seiler, Till, Stilgenbauer, Stephan, Klein-Hitpass, Ludger, Dührsen, Ulrich, Dürig, Jan
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751910/
https://ncbi.nlm.nih.gov/pubmed/24009671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072107
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