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Progranulin Is a Novel Independent Predictor of Disease Progression and Overall Survival in Chronic Lymphocytic Leukemia

Progranulin (Pgrn) is a 88 kDa secreted protein with pleiotropic functions including regulation of cell cycle progression, cell motility, wound repair and tumorigenesis. Using microarray based gene expression profiling we have recently demonstrated that the gene for Pgrn, granulin (GRN), is signific...

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Bibliografiske detaljer
Main Authors: Göbel, Maria, Eisele, Lewin, Möllmann, Michael, Hüttmann, Andreas, Johansson, Patricia, Scholtysik, René, Bergmann, Manuela, Busch, Raymonde, Döhner, Hartmut, Hallek, Michael, Seiler, Till, Stilgenbauer, Stephan, Klein-Hitpass, Ludger, Dührsen, Ulrich, Dürig, Jan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751910/
https://ncbi.nlm.nih.gov/pubmed/24009671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072107
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