SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemia

T-cell prolymphocytic leukemia (T-PLL) is an aggressive malignancy with a median survival of the patients of less than two years. Besides characteristic chromosomal translocations, frequent mutations affect the ATM gene, JAK/STAT pathway members, and epigenetic regulators. We here performed a target...

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Detalhes bibliográficos
Publicado no:Blood Cancer J
Main Authors: Johansson, Patricia, Klein-Hitpass, Ludger, Choidas, Axel, Habenberger, Peter, Mahboubi, Bijan, Kim, Baek, Bergmann, Anke, Scholtysik, René, Brauser, Martina, Lollies, Anna, Siebert, Reiner, Zenz, Thorsten, Dührsen, Ulrich, Küppers, Ralf, Dürig, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802577/
https://ncbi.nlm.nih.gov/pubmed/29352181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-017-0036-5
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