Recurrent mutations in NF-κB pathway components, KMT2D, and NOTCH1/2 in ocular adnexal MALT-type marginal zone lymphomas

The pathogenesis of ocular adnexal marginal zone lymphomas of mucosa-associated lymphatic tissue-type (OAML) is still poorly understood. We analyzed 63 cases of such lymphomas for non-synonymous mutations in 24 candidate genes by amplicon sequencing. We validated frequent mutations in the NF-κB regu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Johansson, Patricia, Klein-Hitpass, Ludger, Grabellus, Florian, Arnold, Georg, Klapper, Wolfram, Pförtner, Roman, Dührsen, Ulrich, Eckstein, Anja, Dürig, Jan, Küppers, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308752/
https://ncbi.nlm.nih.gov/pubmed/27566587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11548
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