Progranulin Is a Novel Independent Predictor of Disease Progression and Overall Survival in Chronic Lymphocytic Leukemia

Progranulin (Pgrn) is a 88 kDa secreted protein with pleiotropic functions including regulation of cell cycle progression, cell motility, wound repair and tumorigenesis. Using microarray based gene expression profiling we have recently demonstrated that the gene for Pgrn, granulin (GRN), is signific...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Göbel, Maria, Eisele, Lewin, Möllmann, Michael, Hüttmann, Andreas, Johansson, Patricia, Scholtysik, René, Bergmann, Manuela, Busch, Raymonde, Döhner, Hartmut, Hallek, Michael, Seiler, Till, Stilgenbauer, Stephan, Klein-Hitpass, Ludger, Dührsen, Ulrich, Dürig, Jan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751910/
https://ncbi.nlm.nih.gov/pubmed/24009671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072107
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