Inhibition of hepatitis B virus (HBV) gene expression and replication by HBx gene silencing in a hydrodynamic injection mouse model with a new clone of HBV genotype B

BACKGROUND: It has been suggested that different hepatitis B virus (HBV) genotypes may have distinct virological characteristics that correlate with clinical outcomes during antiviral therapy and the natural course of infection. Hydrodynamic injection (HI) of HBV in the mouse model is a useful tool...

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Autors principals: Li, Lei, Shen, Hong, Li, Anyi, Zhang, Zhenhua, Wang, Baoju, Wang, Junzhong, Zheng, Xin, Wu, Jun, Yang, Dongliang, Lu, Mengji, Song, Jingjiao
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751867/
https://ncbi.nlm.nih.gov/pubmed/23805945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-214
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