Inhibition of hepatitis B virus (HBV) gene expression and replication by HBx gene silencing in a hydrodynamic injection mouse model with a new clone of HBV genotype B

BACKGROUND: It has been suggested that different hepatitis B virus (HBV) genotypes may have distinct virological characteristics that correlate with clinical outcomes during antiviral therapy and the natural course of infection. Hydrodynamic injection (HI) of HBV in the mouse model is a useful tool...

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Hlavní autoři: Li, Lei, Shen, Hong, Li, Anyi, Zhang, Zhenhua, Wang, Baoju, Wang, Junzhong, Zheng, Xin, Wu, Jun, Yang, Dongliang, Lu, Mengji, Song, Jingjiao
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751867/
https://ncbi.nlm.nih.gov/pubmed/23805945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-214
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