Inhibition of hepatitis B virus (HBV) gene expression and replication by HBx gene silencing in a hydrodynamic injection mouse model with a new clone of HBV genotype B

BACKGROUND: It has been suggested that different hepatitis B virus (HBV) genotypes may have distinct virological characteristics that correlate with clinical outcomes during antiviral therapy and the natural course of infection. Hydrodynamic injection (HI) of HBV in the mouse model is a useful tool...

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Huvudupphovsmän: Li, Lei, Shen, Hong, Li, Anyi, Zhang, Zhenhua, Wang, Baoju, Wang, Junzhong, Zheng, Xin, Wu, Jun, Yang, Dongliang, Lu, Mengji, Song, Jingjiao
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2013
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751867/
https://ncbi.nlm.nih.gov/pubmed/23805945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-214
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