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The dose of HBV genome contained plasmid has a great impact on HBV persistence in hydrodynamic injection mouse model
BACKGROUND: Hydrodynamic injection (HI) of hepatitis B virus (HBV) mouse model is an useful tool for HBV related research in vivo. However, only 40% of C57/BL6 mice injected with 10 μg HBV genome contained plasmid (pAAV-HBV1.2), serum HBsAg more than 6 months and none of the BALB/c mice injected wit...
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| Veröffentlicht in: | Virol J |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5657044/ https://ncbi.nlm.nih.gov/pubmed/29070073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-017-0874-6 |
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