Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia

Chronic hypoxia causes pulmonary hypertension with smooth muscle cell proliferation and matrix deposition in the wall of the pulmonary arterioles. We demonstrate here that hypoxia also induces a pronounced inflammation in the lung before the structural changes of the vessel wall. The proinflammatory...

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Bibliographische Detailangaben
Hauptverfasser: Minamino, Tohru, Christou, Helen, Hsieh, Chung-Ming, Liu, Yuxiang, Dhawan, Vijender, Abraham, Nader G., Perrella, Mark A., Mitsialis, S. Alex, Kourembanas, Stella
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2001
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC37515/
https://ncbi.nlm.nih.gov/pubmed/11447290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161272598
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