Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia

Chronic hypoxia causes pulmonary hypertension with smooth muscle cell proliferation and matrix deposition in the wall of the pulmonary arterioles. We demonstrate here that hypoxia also induces a pronounced inflammation in the lung before the structural changes of the vessel wall. The proinflammatory...

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Detalhes bibliográficos
Main Authors: Minamino, Tohru, Christou, Helen, Hsieh, Chung-Ming, Liu, Yuxiang, Dhawan, Vijender, Abraham, Nader G., Perrella, Mark A., Mitsialis, S. Alex, Kourembanas, Stella
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC37515/
https://ncbi.nlm.nih.gov/pubmed/11447290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161272598
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