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Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia

Chronic hypoxia causes pulmonary hypertension with smooth muscle cell proliferation and matrix deposition in the wall of the pulmonary arterioles. We demonstrate here that hypoxia also induces a pronounced inflammation in the lung before the structural changes of the vessel wall. The proinflammatory...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Minamino, Tohru, Christou, Helen, Hsieh, Chung-Ming, Liu, Yuxiang, Dhawan, Vijender, Abraham, Nader G., Perrella, Mark A., Mitsialis, S. Alex, Kourembanas, Stella
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC37515/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11447290/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.161272598
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